How should I set up my Offense this week for Fantasy Football? Please help fill in holes!?

Well for RB's that is easy since Portis is out this week...just plug in Pierre and Ricky. For the flex spot Nate Burleson is playing excellent this year, I would go with him. TE, with Brees at QB Shockey looks good every week. And Defense, Pittsburg is always top tier when the head and shoulders guy with the beautiful hair is in the line-up